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Acute pyelonephritis is a sudden and severe kidney infection that typically begins in the lower urinary tract, such as the bladder or urethra, and ascends to one or both kidneys. This condition is a type of urinary tract infection (UTI) that involves inflammation and, often, infection of the kidney tissue and renal pelvis. It requires prompt medical attention to prevent potential complications. Symptoms -Fever and chills -Flank pain: Pain in the back or side, often severe -Nausea and vomiting -Painful urination (dysuria) -Frequent, urgent urination -Cloudy or foul-smelling urine -Blood in the urine (hematuria)